Ipamorelin

Name: Ipamorelin
Brand: Canada Peptides
Price: 32.0 CAD
Availability: InStock

$32.00

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This batch of Ipamorelin Growth Hormone Peptide has been third party lab tested and verified for quality.

Contents: Ipamorelin
Form: Powder
Purity: 99.4%

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Weight - 5mg

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Ipamorelin Peptide – 5mg
Ipamorelin is a synthetic pentapeptide classified as a selective growth hormone (GH) secretagogue. It acts as an agonist of the ghrelin receptor (growth hormone secretagogue receptor, GHSR-1a), located in the hypothalamus and anterior pituitary. Through this interaction, Ipamorelin has been investigated for its ability to stimulate pulsatile GH release without substantially affecting other hormones such as ACTH, prolactin, or cortisol.

Overview
Ipamorelin is often regarded as one of the most selective GH secretagogues. Research suggests that it triggers intracellular signaling through G protein–coupled receptor pathways, leading to elevated cyclic AMP and calcium flux in pituitary somatotrophs. This cascade appears to stimulate GH release while minimizing activity on other endocrine axes.

Compared with older GH-releasing peptides, Ipamorelin shows reduced off-target activity, making it a widely studied candidate for models of GH regulation, tissue repair, metabolic balance, and bone health. Its selectivity is of particular interest for research into regeneration and recovery processes, as GH and its downstream mediator IGF-1 are implicated in growth, repair, and metabolism.

Chemical Makeup

Molecular Formula: C38H49N9O5
Molecular Weight: 711.9 g/mol
Amino Acid Sequence: Aib-His-D-2-Nal-D-Phe-Lys-NH2
Other Known Titles: Ipamorelin acetate

Research and Clinical Studies

Growth Hormone Secretion
In human and animal studies, Ipamorelin administration increased GH levels in a dose-dependent manner. Importantly, it did not significantly elevate ACTH, prolactin, or cortisol, supporting its characterization as a selective GH secretagogue.

Bone and Connective Tissue Models
Experimental data suggest that GH and IGF-1 promote bone turnover and collagen synthesis. Ipamorelin has been studied in relation to bone metabolism and connective tissue recovery, where enhanced GH/IGF-1 signaling may support repair and remodeling processes.

Muscle and Recovery
Preclinical models show that GH secretagogues can indirectly stimulate IGF-1, a growth factor associated with protein synthesis, cell proliferation, and muscle recovery. Ipamorelin has been examined in settings of tissue injury for its potential role in accelerating repair.

Metabolic Function
Growth hormone influences lipid and glucose metabolism. Ipamorelin has been studied in metabolic models for its ability to increase GH signaling selectively, potentially contributing to fat utilization while maintaining a neutral effect on other hormone systems.

Ipamorelin peptide is available for research and laboratory purposes only. Not for human consumption.

References

Svensson J, et al. Ipamorelin, a novel GH-releasing peptide: selective GH release in humans. J Clin Endocrinol Metab. 1998;83(3):362–369. https://pubmed.ncbi.nlm.nih.gov/9506726/
Bowers CY. Growth hormone-releasing peptides. J Clin Endocrinol Metab. 1998;83(10):3827–3834. https://pubmed.ncbi.nlm.nih.gov/9768654/
Raun K, et al. Ipamorelin: a novel GH secretagogue. Eur J Endocrinol. 1998;139(5):552–561. https://pubmed.ncbi.nlm.nih.gov/9849810/
Raun K, et al. In vivo selectivity of Ipamorelin. Eur J Endocrinol. 2001;145(1):27–35. https://pubmed.ncbi.nlm.nih.gov/11427506/
Anderson LL, et al. The GH secretagogue receptor and ghrelin mechanisms. Endocr Rev. 2004;25(1):79–108. https://pubmed.ncbi.nlm.nih.gov/14769829/
Kineman RD, et al. The GH/IGF-1 axis and tissue repair. Endocrinology. 2007;148(9):4095–4100. https://pubmed.ncbi.nlm.nih.gov/17569764/
Garcia JM, et al. Ghrelin and GH secretagogues in models of muscle and metabolism. Endocr Dev. 2010;17:87–98. https://pubmed.ncbi.nlm.nih.gov/19955773/
Svensson J, et al. Selective GH release without cortisol or prolactin effects by Ipamorelin. J Clin Endocrinol Metab. 2000;85(8):2811–2816. https://pubmed.ncbi.nlm.nih.gov/10946879/
Colao A, et al. Systemic effects of GH and IGF-1. Nat Rev Endocrinol. 2011;7(6):352–361. https://pubmed.ncbi.nlm.nih.gov/21423247/
Smith RG, et al. Clinical potential of ghrelin receptor agonists. Endocr Dev. 2003;6:159–166. https://pubmed.ncbi.nlm.nih.gov/14714897/

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Frequently Asked Questions

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Every vial we sell comes from a lab that follows current Good Manufacturing Practices (cGMP). That means each step of production is documented and controlled. Before a batch is released, it’s tested by independent third-party labs for purity, identity, and sterility. Certificates of analysis are available so you can see the exact test results.

Yes. The labs we work with use ISO-certified clean rooms where air quality, equipment, and handling procedures are tightly regulated. Staff are trained to pharmaceutical-grade standards. This ensures the peptides are produced in an environment that minimizes contamination risks.

Peptides in lyophilized (freeze-dried) form are stable at room temperature for transport. Once you receive them, refrigeration is recommended to maintain long-term integrity. We package every order securely to prevent damage and ship promptly, so your vials arrive in optimal condition.

We operate under strict in-house protocols that follow current Good Manufacturing Practices (cGMP). That means our team oversees the entire process from sourcing raw amino acids to the final lyophilized vial. Nothing is outsourced or repackaged. This gives us full control over purity, consistency, and sterility, and it’s why we can stand behind every single vial we ship.

Store them in the refrigerator, away from direct light and heat. If you need to keep them longer, some peptides can be stored frozen. Each vial comes with clear handling instructions so you know the proper conditions for stability.

The strongest proof is transparency. For every peptide, we can provide certificates of analysis, manufacturing documentation, and references to the published scientific research behind it. If you ever have questions, we’ll show you the data rather than ask you to take our word for it.

The difference is transparency. Most sites give you a product name and a price. We provide full batch testing, lab documentation, and direct access to certificates of analysis so you don’t have to guess what you’re getting. When you order from us, you know exactly what’s in the vial, where it was made, and how it was verified.

Ipamorelin

Ipamorelin

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